It looks like a friction holding design - friction created by torque - axial force on the locking screw (unknown size) + friction between the contacting surfaces (unknown surface area) on unknown material holding the device static against gravity and the unknown static bending - friction forces.
All you can do is estimate the torque created by your "Thumb Screw" and follow the math for the total friction created and then the force required to break the static friction.
Lot's of unknowns and more than a simple calculation.